OpenEvidence
AI HealthcareFree
Free AI-powered medical search engine for verified clinicians delivering cited, evidence-based answers from peer-reviewed literature in seconds.
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Compare OpenEvidence vs Tempus AI
Both tools in AI Healthcare
Tempus AI
AI HealthcarePaid
Precision medicine platform using AI and genomics to power cancer diagnostics, clinical trial matching, and multimodal data insights for oncology and beyond.
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Pricing
Pricing Comparison
OpenEvidence
Free$0
Full access for verified US clinicians, funded by pharmaceutical ads
Enterprise$Custom
Epic EHR integration and health system-wide deployment
Tempus AI
Genomic Testing$Custom/test
Oncology, hereditary, pharmacogenomic, and MRD panels
Data Licensing$Custom
Multi-year Lens platform contracts for biopharma and research
Enterprise$Custom
Integrated health system and clinical copilot deployment
Features
Feature Comparison
OpenEvidence
Quick Consult (Rapid Answer Mode)Deep Consult (Multi-Source Synthesis)Inline Journal CitationsNEJM and JAMA Content PartnershipAMA and NCCN Guideline AccessAmbient Documentation (Visits)HIPAA-Compliant Doctor DialerICD-10 and Coding IntelligenceLock Screen and Home Screen WidgetsiOS and Android Native AppsWeb Interface AccessEpic EHR Integration (Sutter Health)Evidence Search in Natural LanguageVerified Clinician-Only AccessSOC 2 Type II CertifiedPharmaceutical Ad-Funded Free Access20M+ Monthly Clinical Consultations
Tempus AI
xT DNA Tumor SequencingxF Liquid Biopsy TestingxR RNA-Based TestingHereditary Cancer Risk TestingMinimal Residual Disease (MRD) MonitoringAI Clinical Copilot (Tempus One)Patient Cohort Builder (Lens Platform)Natural Language Cohort QueryBiomarker Discovery EngineClinical Trial Patient MatchingEHR-Integrated Genomic InsightsCare Gap Identification (Tempus Next)De-identified Data LicensingPharmacogenomic TestingCardiology AI ApplicationsRadiology AI IntegrationMultimodal Data Library
Fit
Best For & Not For
OpenEvidence
✅ Best For
✅Verified US physicians, residents, NPs, and PAs who need instant, cited answers to clinical questions during hospital rounds, ED shifts, or primary care visits without the cost of UpToDate. Clinicians who want an AI-native alternative to manual PubMed or guideline searches, especially in time-pressured settings.
❌ Not For
❌Patients or non-clinicians without verified healthcare credentials, as OpenEvidence requires professional verification. Clinicians who need differential diagnosis generation or advanced drug dosing calculators, as those features are not yet available in the core platform.
Tempus AI
✅ Best For
✅Oncologists, precision medicine teams, and research coordinators at academic medical centers and large cancer programs who need comprehensive genomic profiling to guide treatment decisions. Biopharma companies and research organizations looking to license de-identified multimodal clinical data or access Tempus's Lens platform for biomarker discovery and clinical trial optimization.
❌ Not For
❌General practitioners or small practices without oncology focus who do not regularly order genomic testing. Organizations seeking ambient documentation, clinical note generation, or administrative AI tools rather than diagnostics and research data platforms.
Availability
Platform & Accessibility
OpenEvidence
web-basedmobile
Tempus AI
web-basedapi
Use & Audience
Tasks & Who It's For
Integrations
Integrations
OpenEvidence
Other
EpicNEJMJAMAAMA
Tempus AI
Other
EpicOracle HealthAstraZenecaMerck
Use Cases
Real-world Use Cases
OpenEvidence
1
Dr. Nguyen, a hospitalist on call at 2 AM, uses OpenEvidence to quickly check the latest evidence on anticoagulation dosing for a patient with atrial fibrillation and severe renal impairment, getting a cited answer in 8 seconds instead of searching three reference tools.2
A third-year internal medicine resident uses Deep Consult before attending rounds to synthesize all current evidence on immune checkpoint inhibitor toxicity management, arriving with structured answers that impress her attending and reduce rounds time by 20 minutes.3
An NP in a rural clinic without an UpToDate subscription uses OpenEvidence as her daily clinical reference, getting the same evidence quality for free and reducing the number of specialist referrals by consulting guidelines in real time.Tempus AI
1
Dr. Osei, a breast oncologist, orders Tempus xT sequencing on a newly diagnosed patient with triple-negative breast cancer and uses the AI report to identify a BRCA2 variant, immediately qualifying the patient for a PARP inhibitor trial and changing her treatment plan.2
A genomic counselor at a large cancer center uses Tempus's hereditary testing from Ambry Genetics to screen 50 at-risk patients per month for inherited cancer syndromes, enabling preventive interventions before cancer develops.3
A biopharma data scientist builds a precision cohort for an immuno-oncology trial using the Lens platform's natural language query, identifying 800 eligible patients in seconds from millions of de-identified records.Keep Exploring